Director, Braftovi/Mektovi Melanoma Strategy & Indication Lead

ROLE SUMMARY

Pfizer Commercial Oncology is introducing the world to the next era of cancer care. With a growing portfolio of novel therapies, industry-leading R&D, and a goal of delivering eight breakthroughs by 2030 across major cancer types, we're translating cutting-edge science into market-shaping impact. Here, you'll partner with exceptional colleagues across scientific, medical, and manufacturing teams, backed by advanced digital and AI-enabled infrastructure and the authority to accelerate medicines from discovery to delivery. Guided by our values of courage, excellence, equity, and joy, you'll have the opportunity to stretch your skills and build a career that evolves with you—across teams, roles, and the Pfizer enterprise.  Join us to make history — for patients, for their families, for the future. 

BRAFTOVI + MEKTOVI is an established cornerstone of Pfizer Oncology’s Precision Medicine & Thoracic Franchise in BRAF V600E/K-mutant metastatic melanoma. The advanced melanoma treatment landscape is complex and dynamic, with many innovative therapies recently launched and more expected to arrive in the near future. In this environment, the melanoma business is focused on defending its position and growing strategically — maintaining the confidence of high-share prescribers, converting new HCPs, protecting access, growing net revenue and market share while the brand moves through the next stage of its lifecycle. For BRAF-mutant metastatic melanoma patients who need a targeted therapy combination, ensuring BRAFTOVI + MEKTOVI remains a well-understood and accessible option matters. This role bears significant responsibility for HCP intent and therapy uptake.

This is the senior commercial seat for the melanoma indication and the owner of the melanoma-specific goals. You are expected to set and adapt the overall melanoma strategy, own commercial strategy and execution directly, and carry the indication P&L end-to-end — topline, GTN, NPS, forecasting, latest estimates, and the KPI framework the franchise steers by. You drive the melanoma plan by drawing on shared franchise marketing resources and leading through influence across a broad cross-functional matrix. Within that mandate, the role leads 2027 melanoma Strategic Imperatives - (1) focusing on 2L+ targeted therapy patients to maintain high-share prescribers and grow through HCP conversion, and (2) defending access and managing GTN. This role is also responsible for leading MEKTOVI loss-of-exclusivity strategy and planning. The role also serves as the franchise Competitive Intelligence captain across indications.

 

ROLE RESPONSIBILITIES

Lead the melanoma strategy and execution

• Define, adapt, and drive the overall melanoma commercial strategy for BRAFTOVI + MEKTOVI, positioning the brand to defend and strategically grow in a complex and evolving treatment landscape
• Own melanoma tactical planning and execution end-to-end, drawing on shared franchise marketing resources and ensuring tactics ladder to the melanoma strategic imperatives
• Lead the melanoma field-based strategy team (FBST), translating brand strategy into field priorities and pull-through
• Lead cross-functional and leadership updates for the indication; represent melanoma in franchise strategic planning, OP, and LE

Deliver melanoma performance

• Responsible for melanoma revenue, TRx, NPS, and GTN as the accountable indication lead
• Lead the melanoma KPI Measurement Framework, instrumenting on prescriber retention, new-HCP conversion, and leading indicators
• Support melanoma forecasting, latest estimates, and phasing

Strategic Imperative and LOE ownership

• Lead SI#1 — focus on the 2L+ targeted therapy patient to maintain high-share prescribers and grow through HCP conversion
• Finalize and implement melanoma lab alerts to drive timely, actionable HCP engagement at key treatment decision points
• Lead SI#2 — defend access and manage GTN, partnering with the Team Lead on pricing and GTN trade-offs
• Lead MEKTOVI LOE strategy and planning, owning the go-to-market strategy and associated tactics through the loss-of-exclusivity transition
• Coordinate with Payer Marketing, Pricing, Contracting, and Account Marketing to ensure access, contracting, and channel strategies support melanoma goals

Lead competitive intelligence and cross-functional partnership

• Serve as franchise Competitive Intelligence captain across indications, managing the CI vendor partnership; lead melanoma CI strategy and execution, translating insights into brand implications
• Coordinate and collaborate with melanoma cross-functional partners — field sales, TLELs, Medical, Patient Services, RC, Legal, Regulatory, analytics, and agencies — to meet our goals for patients
• Serve as Melanoma RBD & Training liaison
• Develop and coach others, including mentoring junior marketing colleagues

 

BASIC QUALIFICATIONS

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

• Bachelor’s degree with 7+ years, MBA/MS with 7+ years, or PhD with 5+ years of marketing, commercial, or related experience
• US marketing / commercial experience
• Demonstrated ability to develop, adapt, and execute brand strategy that drives measurable growth
• Ownership of a commercial P&L, forecast, or KPI framework, with strong analytical and business acumen
• Strong project leadership across multiple simultaneous priorities, stakeholders, and timelines
• Proven ability to lead and influence cross-functionally without direct authority
• Excellent verbal and written communication, including with senior leadership

OTHER JOB DETAILS

Last Date to Apply for Job: October 30, 2026

Eligible for Relocation Package: No

The annual base salary for this position ranges from $176,600.00 to $294,300.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.  Pfizer is an E-Verify employer.  This position requires permanent work authorization in the United States.

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